Non-Invasive Prenatal Testing

Prenatal Care that feels Safe, Accurate, and provides valuable Insight

“All tests are conducted in compliance with the PCPNDT Act. Sex determination is strictly prohibited and will not be disclosed.”

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What is Non-Invasive Prenatal Testing?

Non-Invasive Prenatal Testing (NIPT, also called NIPS) is a genetic test performed during pregnancy to analyse tiny fragments of fetal DNA (called cell-free DNA) that circulate in the mother’s bloodstream. It helps detect numerical abnormalities responsible for conditions like Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18) and Patau syndrome (Trisomy 13).

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What does it screen for ?

  • Common Trisomies: Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13).
  • Sex Chromosome Conditions: Turner syndrome (X) and Klinefelter syndrome (XXY).
  • Rare autosomal aneuploidies.
  • Advanced NIPT offers: Microdeletion screening for smaller missing pieces of chromosomes (XXXXX).

Who should take this test?

  • NIPT is a valuable and insightful option for all pregnant women, regardless of age or risk factors.
  • It is especially recommended for: Advanced maternal age (35 years or older at delivery), a personal or family history of chromosomal conditions, an abnormal finding on a traditional ultrasound or maternal serum screening test, history of previous miscarriages, and those seeking early and risk-free screening information for chromosomal abnormalities.

Test Specification

Panel coverage

  • Basic NIPT: Trisomy 13, 18, and 21 + sex chromosome abnormalities.
  • Advanced NIPT: All of the above + microdeletions.

Technique

Next generation sequencing

Sensitivity

>99% for Trisomy 13, 18 and 21

Specificity

>99% for Trisomy 13, 18 and 21

Variant type

Copy number variants

Turnaround Time

Basic NIPT 10 days, Advanced NIPT 14 days

Sample type

10mL maternal blood in streck tube

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Why choose OneDNA

Early & Accurate

Non-invasive screening from 10 weeks with >99% sensitivity

Comprehensive Coverage

Detects common trisomies & key microdeletions

Accredited Laboratories

Processed in CAP & NABL certified labs

Advanced NGS Technology

Precise analysis of all chromosomes

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Frequently Asked Questions

Yes. Non-invasive prenatal diagnosis is completely safe because it does not involve needles or instruments entering the womb. Unlike invasive procedures such as amniocentesis, it carries no risk of miscarriage.

Traditional serum screening measures proteins/hormones. NIPT analyzes fetal DNA directly, offering significantly higher accuracy.

No. NIPT screens for chromosomal conditions. The maternal serum alpha-fetoprotein (MSAFP) test or a detailed anatomy ultrasound (around 20 weeks) is used to screen for neural tube defects.

Your doctor will discuss the results with you and refer you for genetic counseling. A diagnostic procedure (CVS or amniocentesis) will be offered to confirm the screening result.

The test can be performed any time after 10 weeks gestation. Your doctor will guide you with the test after your ultrasound, which is an important first step in your prenatal care.

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