PharmaGenecare

Right drug. Right dose. Right for you.

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What is PharmaGenecare?

OneDNA Pharmagenecare analyses your genetic makeup to assess how your body responds to 170+ drugs across 13 key therapy areas including cardiology, oncology, neurology, psychiatry, and more. It helps personalize treatment, reduce side effects, and improve overall drug safety and effectiveness.

How Does It Work?

Pharmagenecare evaluates a person's DNA to determine how they may metabolize or respond to medications, helping guide healthcare providers in selecting appropriate drugs and dosing. Two types of genes are studied:
  • 1. Pharmacodynamic genes: Produce proteins that influence how a medication acts on the body.
  • 2. Pharmacokinetic genes: Produce proteins that affect how the body absorbs, distributes, metabolizes, and eliminates medications.
The test requires a simple, non-invasive sample collection, typically using a buccal (cheek) swab, where a soft swab is gently rubbed inside the cheek to collect cells.

Who can consider testing?

  • 1. Patients who are on multiple medications.
  • 2. Patients who have experienced unexpected side effects.
  • 3. Cancer patients before starting chemotherapy or targeted therapy.
  • 4. Patients with psychiatric conditions being prescribed antidepressants or antipsychotics.

Test specifications

Technique

The test is based on microarray technology, a high throughput genomic approach that enables simultaneous analysis of thousands of genetic markers across the genome.

Platform

Performed on the Illumina Infinium BeadChip (24 BeadChip), a robust and scalable platform designed for efficient processing of multiple samples while maintaining high data quality and consistency.

Bioinformatics & Analysis

Raw data is generated using the Illumina iScan system and further processed through advanced bioinformatics pipelines, including GenomeStudio 2.0 and SNaPpy 2.0.

Coverage

The assay is designed to analyze Single Nucleotide Polymorphisms (SNPs) across the genome.

Accuracy

Demonstrates up to 99.6% accuracy for clinically classified genes, ensuring high confidence in reported results and supporting reliable clinical interpretation.

Sample Type

Requires a non-invasive saliva sample making the test convenient and patient friendly while maintaining high DNA yield and quality.

Precautions

To ensure optimal sample integrity, individuals should avoid eating, drinking, smoking, or chewing gum for at least 30 minutes prior to sample collection.

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Why choose OneDNA

Comprehensive Coverage

Comprehensive testing across both molecular and cytogenetic platforms

Accredited Laboratories

NABL & CAP accredited lab

Support & Care

End-to-end support including genetic counselling and report guidance.

Early & Accurate

High accuracy with advanced technologies and stringent quality controls

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Frequently Asked Questions

While the test can be taken independently, results are most valuable when reviewed with a healthcare provider who can guide medication decisions.

Individuals on multiple medications, those experiencing side effects, cancer patients, and individuals starting psychiatric medications can benefit significantly.

The test helps guide medication choices by showing how your body may process certain drugs, but final decisions should always be made by your doctor based on your overall health.

Yes. In fact, the test can be particularly useful in understanding how your current medications may be working for you.

This is a one time test. Your genetic makeup does not change, so the results remain relevant for life.

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