Nephro Genetics

Go beyond reports to understand your kidney health

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What is Nephro Genetics?

A significant proportion of kidney disorders have a genetic basis contributing to nearly 20% of chronic kidney disease cases in adults, with an even higher impact seen in children. OneDNA’s nephrogenetic testing offers a comprehensive approach to uncover the genetic causes of renal conditions, supporting precise diagnosis, improving clinical insights into disease progression, and enabling tailored treatment and long term management plans.

Which nephrology conditions can be diagnosed?

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  • Chronic kidney disease of unknown cause
  • Inherited kidney disorders (e.g., polycystic kidney disease, Alport syndrome)
  • Nephrotic syndrome and glomerular disorders
  • Tubular disorders (e.g., Bartter syndrome, Gitelman syndrome)
  • Congenital anomalies of the kidney and urinary tract (CAKUT)

Who can consider testing ?

  • Individuals with unexplained or early onset kidney disease
  • Patients with chronic kidney disease of unknown cause
  • Individuals with a family history of kidney disorders
  • Children with congenital kidney or urinary tract anomalies
  • Individuals being evaluated for kidney transplant or donor suitability

Test specifications

Methodology

WES (Next Generation Sequencing)

Specificity & Sensitivity

99-100%

Coverage

80-100x Depth

Sample type

Blood in EDTA

TAT

4 weeks

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Why choose OneDNA

Comprehensive Coverage

Comprehensive testing across both molecular and cytogenetic platforms

Accredited Laboratories

NABL & CAP accredited lab

Support & Care

End-to-end support including genetic counselling and report guidance.

Early & Accurate

High accuracy with advanced technologies and stringent quality controls

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Frequently Asked Questions

Because many kidney diseases have an inherited cause, especially when they start early or have no clear medical explanation.

Regular tests show what is happening. Genetic testing helps explain why it’s happening, which can change how your condition is managed.

Yes. Genetic conditions don’t always show up clearly in family history. Some can appear for the first time or go unnoticed in earlier generations.

No. It’s useful even in early stage or unexplained kidney issues, especially to prevent progression or complications later.

It helps ensure the cause of kidney failure is clearly understood and also helps assess donor compatibility and future risks.

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