Newborn screening

Newborn care that feels safe and reassuring with complete confidence from day one.

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What is Newborn screening?

Newborn screening is a simple, safe heel-prick blood test performed within the first 24–72 hours after birth to detect serious but treatable congenital and metabolic disorders, often before any symptoms appear. The test uses a Dried Blood Spot (DBS) card collected via heel prick and is analysed using advanced technologies including ELISA, TMS, GC-MS, and LC-MSMS at ISO-certified laboratories.

What does it screen for?

  • Screens for a wide range of inherited metabolic and genetic disorders in newborns.
  • Includes thyroid issues, amino acid disorders, organic acidurias, and hemoglobinopathies.
  • Covers conditions like G6PD deficiency, cystic fibrosis, PKU, and thalassemia.
  • Uses advanced technologies like TMS, GC-MS, and LC-MS/MS for accurate detection.
  • Enables early diagnosis and timely treatment to prevent long-term complications.

Who should take this test?

  • All newborns: Recommended for every baby within 24–72 hours of birth, regardless of apparent health.
  • A family history of chromosomal or metabolic disorders.
  • Advanced maternal age (35+) at the time of delivery.
  • An abnormal finding on traditional ultrasound or previous prenatal tests, or a history of a previous anomalous or chromosomally abnormal pregnancy.

Panel Coverage

  • BIO 6: 6 conditions (CH, CAH, G6PD, GAL, CF, Biotinidase).
  • BIO 7: All BIO 6 + Phenylketonuria (PKU).
  • TMS: 45+ parameters (amino acids, urea cycle, acylcarnitines).
  • GC-MS / UOA: 130+ organic acid parameters.

Technology used

  • ELISA & EIA: BIO 6 and BIO 7 panels.
  • Tandem Mass Spectrometry (TMS): Metabolic panels.
  • GC-MS: Organic acid urinary analysis.
  • LC-MS/MS: Plasma amino acids and hemoglobinopathies.

Sensitivity & TAT

  • >99% sensitivity for primary panels.
  • Results in <1 week for BIO, TMS, Plasma AA, and Hb panels.
  • Results in 1 week for GC-MS / UOA.
  • Sample: Heel prick DBS card (most panels).

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Why choose OneDNA

Comprehensive Coverage

Comprehensive testing across both molecular and cytogenetic platforms

Accredited Laboratories

NABL & CAP accredited lab

Support & Care

End-to-end support including genetic counselling and report guidance.

Early & Accurate

High accuracy with advanced technologies and stringent quality controls

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Frequently Asked Questions

Yes. The test is completely safe. It only involves a small heel prick to collect a few drops of blood on a special card. There is no risk to the baby.

A healthcare professional collects a few drops of blood from your baby’s heel on a special Dried Blood Spot (DBS) card. The sample is then analyzed in a certified laboratory using advanced technologies.

It does not prevent diseases, but it enables early detection and early treatment, which can prevent serious complications and improve long-term health outcomes.

Yes. Routine tests check current health status, while newborn screening looks for hidden genetic or metabolic conditions that may appear later in life.

No. It screens for a defined set of treatable conditions, especially metabolic and inherited disorders. It does not test for all possible genetic diseases.

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