Liquid Biopsy Genetic Testing

Track how your cancer changes during treatment.

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What is Liquid Biopsy Genetic Testing?

Liquid biopsy based genetic testing analyzes circulating tumor DNA (ctDNA), circulating tumor cells, or cell free DNA (cfDNA) shed by tumors into the bloodstream. It enables real time, non-invasive genomic profiling without the need for tissue extraction. It is particularly valuable for detecting early stage cancer, monitoring minimal residual disease (MRD), tracking clonal evolution, and identifying resistance mutations during treatment.

Which Liquid Biopsy panels do we offer?

  • Oncomine cfDNA Lung Assay
  • Oncomine cfDNA Pancreatic Cancer Assay
  • Oncomine Precision GX Assay – Liquid Biopsy
  • Onco Panel Liquid Biopsy (SNV, CNV, Fusion + BRCA)
  • Ultra Solid + Liquid Biopsy (Comprehensive Genomic Profiling with Tissue & cfDNA + PD-L1)

Who can consider testing ?

  • Advanced or metastatic cancer patients
  • When tissue biopsy is not feasible (deep, inaccessible tumors or patients unfit for invasive procedures)
  • Disease progression or treatment resistance
  • Insufficient or exhausted tissue sample
  • Monitoring treatment response

Key Parameters covered under the panels

Oncomine cf DNA Lung Assay

DNA+RNA

Oncomine cf DNA Pancreatic Cancer Assay

DNA+RNA

Oncomine precision GX Assay - Liquid Bx -

DNA mutations, CNVs, RNA Fusion

Onco panel Liquid Bx (SNV, CNV, Fusion+BRCA)

42 Genes, Except MSI

Ultra Solid + Liquid Bx (Comprehensive Genomic Profiling Concurrent With Tissue & cf-DNA + PDL1

546 genes - tMB, MSI, HRR Tissue 55 genes - CF dNA, pDL - 1 by DAKO

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Why choose OneDNA

Comprehensive Coverage

Comprehensive testing across both molecular and cytogenetic platforms

Accredited Laboratories

NABL & CAP accredited lab

Support & Care

End-to-end support including genetic counselling and report guidance.

Early & Accurate

High accuracy with advanced technologies and stringent quality controls

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Frequently Asked Questions

It helps track how your cancer is responding and can identify new mutations or resistance, allowing doctors to adjust treatment in real time.

Yes, in many cases it can detect minimal residual disease (MRD) very small traces of cancer even before symptoms or scans pick it up.

It’s highly advanced, but not perfect. It works best when tumors are actively shedding DNA into the blood. Sometimes, a tissue biopsy may still be needed for confirmation.

It’s widely used in cancers like lung cancer (e.g., EGFR mutations) and in assessing markers like microsatellite instability (MSI), among others.

It can detect changes at a molecular level much earlier than imaging scans, helping doctors act sooner if needed.

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